7RVX
Structure of the SARS-CoV-2 main protease in complex with inhibitor MPI24
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 3C-like proteinase | polymer | 306 | 33857.5 | 2 | UniProt (P0DTD1) Pfam (PF05409) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2 COVID-19 virus) | Main protease, 3CL protease |
2 | A, B | benzyl [(1S)-1-cyclopropyl-2-{[(2S)-3-cyclopropyl-1-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-1-oxopropan-2-yl]amino}-2-oxoethyl]carbamate | non-polymer | 500.6 | 2 | Chemie (7YI) | |||
3 | water | water | 18.0 | 229 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 67715.1 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1001.2 | |
All* | Total formula weight | 68716.3 |