7Q5O
Bromodomain-containing 2 BD2 in complex with the inhibitor CRCM5484
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 2 | polymer | 110 | 12926.9 | 1 | UniProt (P25440) Pfam (PF00439) In PDB | Homo sapiens (human) | O27.1.1,Really interesting new gene 3 protein |
| 2 | A | 2-[[11-ethanoyl-4-(furan-2-ylmethyl)-3-oxidanylidene-8-thia-4,6,11-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),5-trien-5-yl]sulfanyl]-~{N}-(2-methylpyridin-3-yl)ethanamide | non-polymer | 509.6 | 1 | Chemie (8M6) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | water | water | 18.0 | 159 | Chemie (HOH) |
Sequence modifications
A: 346 - 454 (UniProt: P25440)
| PDB | External Database | Details |
|---|---|---|
| Ala 345 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12926.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 695.8 | |
| All* | Total formula weight | 13622.7 |
