7P5V
Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Volume-regulated anion channel subunit LRRC8A | polymer | 810 | 94239.4 | 6 | UniProt (Q80WG5) Pfam (PF12534) Pfam (PF13855) In PDB | Mus musculus (Mouse) | Leucine-rich repeat-containing protein 8A,Protein ebouriffe,ebo |
2 | G, H, I, J, K... | Synthetic nanobody Sb1 | polymer | 144 | 16036.6 | 6 | synthetic construct |
Sequence modifications
A, B, C, D, E, F: 15 - 808 (UniProt: Q80WG5)
PDB | External Database | Details |
---|---|---|
Met 1 | - | initiating methionine |
Ile 2 | - | expression tag |
Pro 3 | - | expression tag |
Val 4 | - | expression tag |
Thr 5 | - | expression tag |
Glu 6 | - | expression tag |
Leu 7 | - | expression tag |
Arg 8 | - | expression tag |
Tyr 9 | - | expression tag |
Phe 10 | - | expression tag |
Ala 11 | - | expression tag |
Asp 12 | - | expression tag |
Thr 13 | - | expression tag |
Gln 14 | - | expression tag |
Gln 809 | - | expression tag |
Ala 810 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 661655.9 | |
All* | Total formula weight | 661655.9 |