7NAK
Cryo-EM structure of activated human SARM1 in complex with NMN and 1AD (TIR:1AD)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | D, C, G, B, A... | NAD(+) hydrolase SARM1 | polymer | 697 | 76471.5 | 8 | UniProt (Q6SZW1) Pfam (PF07647) Pfam (PF13676) In PDB | Homo sapiens (Human) | hSARM1,NADP(+) hydrolase SARM1,Sterile alpha and Armadillo repeat protein,Sterile alpha and TIR motif-containing protein 1,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog,HsTIR |
2 | D, C, G, B, A... | [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(5-iodanylisoquinolin-2-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | non-polymer | 797.4 | 8 | Chemie (1QD) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 611771.8 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 6378.9 | |
All* | Total formula weight | 618150.7 |