7NAJ
Crystal structure of the TIR domain from human SARM1 in complex with ara-2'F-ADPR
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Sterile alpha and TIR motif-containing protein 1 | polymer | 144 | 16333.7 | 2 | UniProt (Q6SZW1) Pfam (PF13676) In PDB | Homo sapiens (Human) | Sterile alpha and Armadillo repeat protein,Sterile alpha motif domain-containing protein 2,SAM domain-containing protein 2,Tir-1 homolog |
2 | A, B | 1,4-anhydro-2-deoxy-2-fluoro-5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-D-arabinitol | non-polymer | 296.1 | 2 | Chemie (1LK) | |||
3 | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A, B: 560 - 700 (UniProt: Q6SZW1)
PDB | External Database | Details |
---|---|---|
Ser 557 | - | expression tag |
Asn 558 | - | expression tag |
Ala 559 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 32667.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 592.2 | |
All* | Total formula weight | 33259.6 |