7N4J
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2173.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Spike protein S1 | polymer | 205 | 23073.8 | 1 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV SARS-CoV-2) | |
| 2 | H | WRAIR-2173 antibody Fab heavy chain | polymer | 236 | 25308.5 | 1 | Homo sapiens (Human) | ||
| 3 | L | WRAIR-2173 antibody Fab light chain | polymer | 218 | 22874.3 | 1 | Homo sapiens (Human) | ||
| 4 | B | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | water | water | 18.0 | 281 | Chemie (HOH) |
Sequence modifications
A: 331 - 527 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 528 | - | expression tag |
| Ser 529 | - | expression tag |
| His 530 | - | expression tag |
| His 531 | - | expression tag |
| His 532 | - | expression tag |
| His 533 | - | expression tag |
| His 534 | - | expression tag |
| His 535 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 71256.5 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 586.5 | |
| All* | Total formula weight | 71843.1 |
