7MRH
Crystal structure of the first bromodomain (BD1) of human BRDT bound to NC-II-259
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Bromodomain testis-specific protein | polymer | 113 | 13319.4 | 2 | UniProt (Q58F21) Pfam (PF00439) In PDB | Homo sapiens (Human) | Cancer/testis antigen 9,CT9,RING3-like protein |
| 2 | A, B | N-[3-(2-methyl-1-oxo-1,2-dihydroisoquinolin-4-yl)phenyl]ethanesulfonamide | non-polymer | 342.4 | 2 | Chemie (ZMJ) | |||
| 3 | water | water | 18.0 | 168 | Chemie (HOH) |
Sequence modifications
A, B: 29 - 137 (UniProt: Q58F21)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Ala 26 | - | expression tag |
| Ala 27 | - | expression tag |
| Ser 28 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26638.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 684.8 | |
| All* | Total formula weight | 27323.6 |
