7MIX
Human N-type voltage-gated calcium channel Cav2.2 in the presence of ziconotide at 3.0 Angstrom resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Voltage-dependent N-type calcium channel subunit alpha-1B | polymer | 2339 | 262831.8 | 1 | UniProt (Q00975) Pfam (PF00520) Pfam (PF16905) Pfam (PF08763) In PDB | Homo sapiens (Human) | Brain calcium channel III,BIII,Calcium channel,L type,alpha-1 polypeptide isoform 5,Voltage-gated calcium channel subunit alpha Cav2.2 |
| 2 | B | Omega-conotoxin MVIIA | polymer | 25 | 2652.2 | 1 | UniProt (P05484) Pfam (PF02950) In PDB | Conus magus | SNX-111, Ziconotide |
| 3 | D | Voltage-dependent calcium channel subunit alpha-2/delta-1 | polymer | 1103 | 124692.5 | 1 | UniProt (P54289) Pfam (PF08399) Pfam (PF00092) Pfam (PF08473) In PDB | Homo sapiens (Human) | Voltage-gated calcium channel subunit alpha-2/delta-1 |
| 4 | C | Voltage-dependent L-type calcium channel subunit beta-3 | polymer | 484 | 54607.9 | 1 | UniProt (P54284) Pfam (PF12052) Pfam (PF00625) In PDB | Homo sapiens (Human) | CAB3,Calcium channel voltage-dependent subunit beta 3 |
| 5 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 627.6 | 1 | In PDB GlyTouCan (G47362BJ) | |||
| 6 | J, P, S | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 7 | L | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 830.8 | 1 | In PDB GlyTouCan (G01361SX) | |||
| 8 | A, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 9 | A, D | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 10 | A | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
| 11 | A | CHOLESTEROL | non-polymer | 386.7 | 5 | Chemie (CLR) | |||
| 12 | A | 1,2-Distearoyl-sn-glycerophosphoethanolamine | non-polymer | 748.1 | 2 | Chemie (3PE) | |||
| 13 | A | [(2R)-1-octadecanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phospho ryl]oxy-propan-2-yl] (8Z)-icosa-5,8,11,14-tetraenoate | non-polymer | 1047.1 | 1 | Chemie (PT5) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 444784.3 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2731.6 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 6193.7 | |
| All* | Total formula weight | 453709.6 |
