7M2O
Crystal structure of Human Glycolate Oxidase with Inhibitor Compound 15
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Hydroxyacid oxidase 1 | polymer | 387 | 42640.1 | 1 | UniProt (Q9UJM8) Pfam (PF01070) In PDB | Homo sapiens (Human) | HAOX1,Glycolate oxidase,GOX |
2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
3 | A | 5-[(5'-{1-(4-carboxy-1,3-thiazol-2-yl)-5-(cyclopropylmethyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]-1H-pyrazol-3-yl}-2'-fluoro[1,1'-biphenyl]-4-yl)oxy]-1H-1,2,3-triazole-4-carboxylic acid | non-polymer | 733.7 | 1 | Chemie (YOJ) | |||
4 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
5 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
6 | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A: 1 - 370 (UniProt: Q9UJM8)
PDB | External Database | Details |
---|---|---|
Gly -16 | - | expression tag |
Ser -15 | - | expression tag |
His -14 | - | expression tag |
Met -13 | - | expression tag |
Ala -12 | - | expression tag |
Ser -11 | - | expression tag |
Met -10 | - | expression tag |
Thr -9 | - | expression tag |
Gly -8 | - | expression tag |
Gly -7 | - | expression tag |
Gln -6 | - | expression tag |
Gln -5 | - | expression tag |
Met -4 | - | expression tag |
Gly -3 | - | expression tag |
Arg -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42640.1 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1756.7 | |
All* | Total formula weight | 44396.8 |