7L0J

Structure of AMH bound to AMHR2-ECD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Muellerian-inhibiting factor	polymer	109	11659.4	1	UniProt (P03971) Pfam (PF00019) In PDB	Homo sapiens (Human)	Anti-Muellerian hormone,AMH,Muellerian-inhibiting substance,MIS
2	B	Anti-Muellerian hormone type-2 receptor	polymer	111	12192.7	1	UniProt (Q16671) In PDB	Homo sapiens (Human)	Anti-Muellerian hormone type II receptor,AMH type II receptor,MIS type II receptor,MRII
3	B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)
4	B	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)

Sequence modifications

A: 459 - 560 (UniProt: P03971)

PDB	External Database	Details
Ser 452	-	expression tag
Ala 453	-	expression tag
Gly 454	-	expression tag
Ala 455	-	expression tag
Thr 456	-	expression tag
Ala 457	-	expression tag
Ala 458	-	expression tag
Ala 515	Val 515	engineered mutation

B: 18 - 124 (UniProt: Q16671)

PDB	External Database	Details
Gly 14	-	expression tag
Pro 15	-	expression tag
His 16	-	expression tag
Met 17	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	23852.1
Non-Polymers*	Number of molecules	2
	Total formula weight	317.3
All*	Total formula weight	24169.4

*Water molecules are not included.