7KLS
Dihydrodipicolinate synthase (DHDPS) from C.jejuni, H59A mutant with pyruvate bound in the active site and L-lysine bound at the allosteric site
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | 4-hydroxy-tetrahydrodipicolinate synthase | polymer | 310 | 34118.2 | 6 | UniProt (Q9PPB4) Pfam (PF00701) In PDB | Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) | HTPA synthase |
2 | A, B, C, D, E... | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 6 | Chemie (PGE) | |||
3 | A, C, E | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
4 | F, A, C, D, E | ACETATE ION | non-polymer | 59.0 | 7 | Chemie (ACT) | |||
5 | F, A, B, C, D... | LYSINE | non-polymer | 147.2 | 6 | Chemie (LYS) | |||
6 | water | water | 18.0 | 268 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 298 (UniProt: Q9PPB4)
PDB | External Database | Details |
---|---|---|
Met -11 | - | expression tag |
Arg -10 | - | expression tag |
Gly -9 | - | expression tag |
Ser -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 59 | His 59 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 204709.1 | |
Non-Polymers* | Number of molecules | 22 |
Total formula weight | 2270.4 | |
All* | Total formula weight | 206979.6 |