7KIR
Crystal structure of inositol polyphosphate 1-phosphatase (INPP1) D54A mutant in complex with inositol (1,4)-bisphosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Inositol polyphosphate 1-phosphatase | polymer | 400 | 43932.9 | 1 | UniProt (P21327) Pfam (PF00459) In PDB | Bos taurus (Bovine) | IPPase |
| 2 | A | D-MYO-INOSITOL-1,4-BISPHOSPHATE | non-polymer | 340.1 | 1 | Chemie (2IP) | |||
| 3 | A | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 4 | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A: 1 - 400 (UniProt: P21327)
| PDB | External Database | Details |
|---|---|---|
| Ala 54 | Asp 54 | engineered mutation |
| Leu 84 | Phe 84 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43932.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 420.3 | |
| All* | Total formula weight | 44353.2 |
