7JUK
Crystal structure of PTEN with a tetra-phosphorylated tail (4p-crPTEN-13sp-T2, SDTTDSDPENEG)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | polymer | 349 | 40886.4 | 1 | UniProt (P60484) Pfam (PF00102) Pfam (PF10409) In PDB | Homo sapiens (Human) | Mutated in multiple advanced cancers 1,Phosphatase and tensin homolog |
| 2 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
A: 7 - 309 (UniProt: P60484)
A: 310 - 353 (UniProt: P60484)
A: 365 - 377 (UniProt: P60484)
| PDB | External Database | Details |
|---|---|---|
| Met 6 | - | initiating methionine |
A: 365 - 377 (UniProt: P60484)
| PDB | External Database | Details |
|---|---|---|
| Thr 354 | - | linker |
| Gly 355 | - | linker |
| Gly 356 | - | linker |
| Gly 357 | - | linker |
| Ser 358 | - | linker |
| Gly 359 | - | linker |
| Gly 360 | - | linker |
| Thr 361 | - | linker |
| Gly 362 | - | linker |
| Gly 363 | - | linker |
| Cys 364 | - | linker |
| Gly 378 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40886.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 40981.4 |
