7JQB

SARS-CoV-2 Nsp1 and rabbit 40S ribosome complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	rRNA	polymer	1869	602777.9	1		Oryctolagus cuniculus (Rabbit)
2	a	eS25	polymer	125	13776.2	1	UniProt (G1TDB3) Pfam (PF03297) In PDB	Oryctolagus cuniculus (Rabbit)
3	B	40S ribosomal protein SA	polymer	295	32958.0	1	UniProt (G1TLT8) Pfam (PF00318) Pfam (PF16122) In PDB	Oryctolagus cuniculus (Rabbit)	37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
4	b	40S ribosomal protein S26	polymer	115	13047.5	1	UniProt (G1TFE8) Pfam (PF01283) In PDB	Oryctolagus cuniculus (Rabbit)
5	C	eS1	polymer	264	30002.1	1	UniProt (G1SS70) Pfam (PF01015) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S3a
6	D	uS5	polymer	293	31327.4	1	Pfam (PF00333) Pfam (PF03719) UniProt (by SIFTS) (P15880) In PDB	Oryctolagus cuniculus (Rabbit)
7	d	eS28	polymer	69	7855.1	1	UniProt (G1TIB4) Pfam (PF01200) In PDB	Oryctolagus cuniculus (Rabbit)	Ribosomal protein S28
8	E	Ribosomal protein S3	polymer	243	26715.3	1	UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) In PDB	Oryctolagus cuniculus (Rabbit)
9	f	eS30	polymer	133	14498.9	1	UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S30
10	G	uS7	polymer	204	22913.5	1	UniProt (G1TFM5) Pfam (PF00177) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S5
11	g	eS31	polymer	156	18004.0	1	UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599) UniProt (by SIFTS) (P62979) In PDB	Oryctolagus cuniculus (Rabbit)	Ribosomal protein S27a
12	H	eS6	polymer	249	28751.9	1	UniProt (G1TM55) Pfam (PF01092) UniProt (by SIFTS) (A0A5K1UJS7) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S6
13	h	RACK1	polymer	317	35115.7	1	UniProt (G1SJB4) Pfam (PF00400) In PDB	Oryctolagus cuniculus (Rabbit)
14	I	eS7	polymer	194	22168.9	1	UniProt (G1SVB0) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S7
15	J	eS8	polymer	208	24263.4	1	UniProt (G1TJW1) Pfam (PF01201) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S8
16	K	uS4	polymer	194	22641.6	1	UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479) In PDB	Oryctolagus cuniculus (Rabbit)	Ribosomal protein S9
17	L	S10_plectin domain-containing protein	polymer	165	18933.8	1	UniProt (G1TPV3) Pfam (PF03501) In PDB	Oryctolagus cuniculus (Rabbit)
18	N	eS12	polymer	132	14539.0	1	UniProt (G1SFR8) Pfam (PF01248) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S12
19	Q	uS19	polymer	145	17049.2	1	UniProt (G1U0Q2) Pfam (PF00203) In PDB	Oryctolagus cuniculus (Rabbit)
20	R	Uncharacterized protein	polymer	146	16477.4	1	UniProt (G1SGX4) Pfam (PF00380) In PDB	Oryctolagus cuniculus (Rabbit)
21	S	eS17	polymer	135	15552.1	1	UniProt (G1TU13) Pfam (PF00833) In PDB	Oryctolagus cuniculus (Rabbit)
22	T	uS13	polymer	152	17759.8	1	UniProt (G1TPG3) Pfam (PF00416) In PDB	Oryctolagus cuniculus (Rabbit)
23	U	Uncharacterized protein	polymer	145	16106.6	1	UniProt (G1TN62) Pfam (PF01090) In PDB	Oryctolagus cuniculus (Rabbit)
24	V	uS10	polymer	119	13398.8	1	UniProt (G1SIZ2) Pfam (PF00338) In PDB	Oryctolagus cuniculus (Rabbit)
25	W	40S ribosomal protein S21	polymer	83	9124.4	1	UniProt (G1TM82) Pfam (PF01249) UniProt (by SIFTS) (P63220) In PDB	Oryctolagus cuniculus (Rabbit)
26	Z	40S ribosomal protein S24	polymer	130	15107.9	1	UniProt (A0A5F9CBF4) Pfam (PF01282) UniProt (by SIFTS) (G1T3D8) In PDB	Oryctolagus cuniculus (Rabbit)
27	F	Host translation inhibitor nsp1	polymer	36	4100.4	1	UniProt (P0DTD1) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	Leader protein,Non-structural protein 1,nsp1
28	M	40S ribosomal protein S4	polymer	263	29658.9	1	UniProt (G1TK17) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) In PDB	Oryctolagus cuniculus (Rabbit)
29	O	uS17	polymer	158	18468.8	1	UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S11
30	P	uS15	polymer	151	17259.4	1	UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312) UniProt (by SIFTS) (P62277) In PDB	Oryctolagus cuniculus (Rabbit)	Ribosomal protein S13
31	X	Uncharacterized protein	polymer	168	18134.0	1	UniProt (G1U472) Pfam (PF00411) UniProt (by SIFTS) (G1T1F0) In PDB	Oryctolagus cuniculus (Rabbit)
32	Y	uS8	polymer	130	14865.6	1	UniProt (G1TG89) Pfam (PF00410) In PDB	Oryctolagus cuniculus (Rabbit)	Ribosomal protein S15a
33	c	Uncharacterized protein	polymer	143	15844.7	1	UniProt (G1SZ47) Pfam (PF00164) In PDB	Oryctolagus cuniculus (Rabbit)
34	e	eS27	polymer	84	9480.2	1	UniProt (G1TZ76) Pfam (PF01667) In PDB	Oryctolagus cuniculus (Rabbit)	40S ribosomal protein S27

Sequence modifications

B: 1 - 295 (UniProt: G1TLT8)

PDB	External Database	Details
Thr 114	Ala 114	conflict

b: 1 - 115 (UniProt: G1TFE8)

PDB	External Database	Details
Arg 28	Cys 28	conflict
Ala 56	Val 56	conflict
Arg 109	Pro 109	conflict

J: 1 - 208 (UniProt: G1TJW1)

PDB	External Database	Details
Arg 47	Gly 47	conflict

U: 1 - 145 (UniProt: G1TN62)

PDB	External Database	Details
Gly 119	Trp 119	conflict

W: 1 - 83 (UniProt: G1TM82)

PDB	External Database	Details
Asn 3	Ser 3	conflict
Asp 4	Asn 4	conflict
Gln 33	Pro 33	conflict
Phe 50	Ser 50	conflict
Ala 75	Ser 75	conflict
Asp 76	His 76	conflict
Lys 81	Gln 81	conflict

Contents of the asymmetric unit

Polymers	Number of chains	34
	Total formula weight	1228678.2
All*	Total formula weight	1228678.2

*Water molecules are not included.