7JM7

Structure of human CLC-7/OSTM1 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	B, D	Osteopetrosis-associated transmembrane protein 1	polymer	334	37290.6	2	UniProt (Q86WC4) Pfam (PF09777) In PDB	Homo sapiens (Human)	Chloride channel 7 beta subunit
2	A, C	H(+)/Cl(-) exchange transporter 7	polymer	805	88773.9	2	UniProt (P51798) Pfam (PF00654) Pfam (PF00571) In PDB	Homo sapiens (Human)	Chloride channel 7 alpha subunit,Chloride channel protein 7,ClC-7
3	E, H	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
4	F, G, I, J	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	4	In PDB GlyTouCan (G42666HT)
5	B, D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	8	Chemie (NAG)
6	A, C	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
7	A, C	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
8	C, A	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
9	C, A	(2R)-3-{[(R)-hydroxy{[(1S,2R,3S,4S,5R,6R)-2,3,4,6-tetrahydroxy-5-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dinonanoate	non-polymer		694.6	2	Chemie (0J1)
10		water	water		18.0	36	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	252128.9
Branched	Number of molecules	6
	Total formula weight	3519.3
Non-Polymers*	Number of molecules	20
	Total formula weight	4434.6
All*	Total formula weight	260082.8

*Water molecules are not included.