7EZP
Indole-2-carboxylic acid derivatives as allosteric inhibitors of fructose-1,6-bisphosphatase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Fructose-1,6-bisphosphatase 1 | polymer | 338 | 36887.4 | 4 | UniProt (P09467) Pfam (PF00316) Pfam (PF18913) In PDB | Homo sapiens (Human) | FBPase 1,D-fructose-1,6-bisphosphate 1-phosphohydrolase 1,Liver FBPase |
| 2 | A, B, C, D | 1,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 4 | Chemie (FBP) | |||
| 3 | A, B, C, D | 3-(3-hydroxy-3-oxopropyl)-5-(2-methylpropyl)-7-nitro-1H-indole-2-carboxylic acid | non-polymer | 334.3 | 4 | Chemie (0GI) | |||
| 4 | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147549.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2697.8 | |
| All* | Total formula weight | 150247.5 |
