7DYQ
Crystal structure of histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Lysine-specific demethylase 4D | polymer | 330 | 38093.2 | 1 | UniProt (Q6B0I6) Pfam (PF02375) Pfam (PF02373) In PDB | Homo sapiens (Human) | JmjC domain-containing histone demethylation protein 3D,Jumonji domain-containing protein 2D,[histone H3]-trimethyl-L-lysine(9) demethylase 4D,Histone lysine demethylase 4D |
| 2 | A | 5-hydroxy-2-methylpyrazolo[1,5-a]pyrido[3,2-e]pyrimidine-3-carbonitrile | non-polymer | 225.2 | 1 | Chemie (HR0) | |||
| 3 | A | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) | |||
| 4 | water | water | 18.0 | 302 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38093.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 281.1 | |
| All* | Total formula weight | 38374.2 |
