7DSV
Structure of a human NHE1-CHP1 complex under pH 6.5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Sodium/hydrogen exchanger 1 | polymer | 472 | 52893.4 | 2 | UniProt (P19634) Pfam (PF00999) In PDB | Homo sapiens (Human) | APNH,Na(+)/H(+) antiporter,amiloride-sensitive,Na(+)/H(+) exchanger 1,NHE-1,Solute carrier family 9 member 1 |
| 2 | D, C | Calcineurin B homologous protein 1 | polymer | 185 | 21369.8 | 2 | UniProt (Q99653) Pfam (PF00036) In PDB | Homo sapiens (Human) | Calcineurin B-like protein,Calcium-binding protein CHP,Calcium-binding protein p22,EF-hand calcium-binding domain-containing protein p22 |
| 3 | A, B | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine | non-polymer | 760.1 | 16 | Chemie (LBN) |
Sequence modifications
D, C: 11 - 195 (UniProt: Q99653)
| PDB | External Database | Details |
|---|---|---|
| Ala 171 | Ile 171 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 148526.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 12161.2 | |
| All* | Total formula weight | 160687.6 |
