7BVB

Crystal structure of UDP-N-acetylmuramic Acid L-alanine ligase (MurC) from Mycobacterium bovis in complex with UDP-N-acetylglucosamine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	UDP-N-acetylmuramate--L-alanine ligase	polymer	519	54402.7	2	UniProt (P65473) Pfam (PF01225) Pfam (PF08245) Pfam (PF02875) In PDB	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (Mycobacterium tuberculosis variant bovis AF2122/97)	UDP-N-acetylmuramoyl-L-alanine synthetase
2	A, B	URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE	non-polymer		607.4	2	Chemie (UD1)
3	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
4		water	water		18.0	76	Chemie (HOH)

Sequence modifications

A, B: 1 - 494 (UniProt: P65473)

PDB	External Database	Details
Met -24	-	initiating methionine
Ser -23	-	expression tag
Tyr -22	-	expression tag
Tyr -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Asp -14	-	expression tag
Tyr -13	-	expression tag
Asp -12	-	expression tag
Ile -11	-	expression tag
Pro -10	-	expression tag
Thr -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	108805.5
Non-Polymers*	Number of molecules	4
	Total formula weight	1345.5
All*	Total formula weight	110151.0

*Water molecules are not included.