7BTF

SARS-CoV-2 RNA-dependent RNA polymerase in complex with cofactors in reduced condition

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase	polymer	942	108162.5	1	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein,Pol,RdRp,Non-structural protein 12,nsp12,SARS-CoV-2 NSP12
2	C	Non-structural protein 7	polymer	83	9248.8	1	UniProt (P0DTD1) Pfam (PF08716) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein,nsp7,SARS-CoV-2 NSP7
3	B, D	Non-structural protein 8	polymer	198	21903.0	2	UniProt (P0DTD1) Pfam (PF08717) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein,nsp8,SARS-CoV-2 NSP8
4	A	ZINC ION	non-polymer		65.4	2	Chemie (ZN)

Sequence modifications

A: 1 - 932 (UniProt: P0DTD1)

PDB	External Database	Details
His 933	-	expression tag
His 934	-	expression tag
His 935	-	expression tag
His 936	-	expression tag
His 937	-	expression tag
His 938	-	expression tag
His 939	-	expression tag
His 940	-	expression tag
His 941	-	expression tag
His 942	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	161217.4
Non-Polymers*	Number of molecules	2
	Total formula weight	130.8
All*	Total formula weight	161348.2

*Water molecules are not included.