7BPZ

X-ray structure of human PPARalpha ligand binding domain-bezafibrate-SRC1 coactivator peptide co-crystals obtained by soaking

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Peroxisome proliferator-activated receptor alpha	polymer	273	30856.1	2	UniProt (Q07869) Pfam (PF00104) In PDB	Homo sapiens
2	B, D	15-meric peptide from Nuclear receptor coactivator 1	polymer	15	1848.2	2	UniProt (Q15788) In PDB	Homo sapiens
3	A, C	2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID	non-polymer		361.8	2	Chemie (PEM)
4		water	water		18.0	8	Chemie (HOH)

Sequence modifications

A, C: 200 - 468 (UniProt: Q07869)

PDB	External Database	Details
Gly 196	-	expression tag
Ser 197	-	expression tag
His 198	-	expression tag
Met 199	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	65408.5
Non-Polymers*	Number of molecules	2
	Total formula weight	723.6
All*	Total formula weight	66132.1

*Water molecules are not included.