7AMV
Atomic structure of the poxvirus transcription pre-initiation complex in the initially melted state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA-directed RNA polymerase 147 kDa polypeptide | polymer | 1286 | 146995.7 | 1 | UniProt (Q1PIV1) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) In PDB | Vaccinia virus GLV-1h68 | |
| 2 | B | DNA-directed RNA polymerase | polymer | 1164 | 133526.9 | 1 | UniProt (Q49PH2) Pfam (PF04560) Pfam (PF12415) Pfam (PF04565) Pfam (PF04567) Pfam (PF00562) In PDB | Vaccinia virus GLV-1h68 | |
| 3 | C | DNA-directed RNA polymerase 35 kDa subunit | polymer | 305 | 35430.7 | 1 | UniProt (Q49PG1) Pfam (PF03396) In PDB | Vaccinia virus GLV-1h68 | |
| 4 | E | DNA-directed RNA polymerase subunit | polymer | 185 | 21365.7 | 1 | UniProt (A4GDF1) Pfam (PF05273) In PDB | Vaccinia virus GLV-1h68 | |
| 5 | F | DNA-directed RNA polymerase 19 kDa subunit | polymer | 164 | 19020.1 | 1 | UniProt (Q49QC8) Pfam (PF05320) In PDB | Vaccinia virus GLV-1h68 | |
| 6 | G | DNA-directed RNA polymerase 18 kDa subunit | polymer | 161 | 17917.2 | 1 | UniProt (Q49PL6) Pfam (PF03293) In PDB | Vaccinia virus GLV-1h68 | |
| 7 | I | Protein H4 | polymer | 795 | 93667.6 | 1 | UniProt (Q1PIU7) Pfam (PF03294) In PDB | Vaccinia virus GLV-1h68 | RNA polymerase-associated transcription-specificity factor RAP94,RPO-associated protein of 94 kDa |
| 8 | J | DNA-directed RNA polymerase 7 kDa subunit | polymer | 63 | 7299.7 | 1 | UniProt (Q49QI2) Pfam (PF05864) In PDB | Vaccinia virus GLV-1h68 | |
| 9 | K | ETF large subunit | polymer | 710 | 82398.9 | 1 | UniProt (Q49QC6) Pfam (PF04441) In PDB | Vaccinia virus GLV-1h68 | Early transcription factor 82 kDa subunit,VETF A7 subunit |
| 10 | N | Synthetic promoter DNA oligomer, non-template strand | polymer | 60 | 18417.9 | 1 | Vaccinia virus GLV-1h68 | ||
| 11 | S | DNA-directed RNA polymerase 30 kDa polypeptide | polymer | 259 | 29834.4 | 1 | UniProt (H2DZ00) Pfam (PF12410) Pfam (PF01096) In PDB | Vaccinia virus GLV-1h68 | |
| 12 | T | Synthetic promoter DNA oligomer, template strand | polymer | 60 | 18547.9 | 1 | Vaccinia virus GLV-1h68 | ||
| 13 | W | ATP-dependent helicase VETFS | polymer | 637 | 73923.6 | 1 | UniProt (Q49QE8) Pfam (PF04851) Pfam (PF00271) In PDB | Vaccinia virus GLV-1h68 | ETF small subunit,Early transcription factor 70 kDa subunit,VETF D6 subunit |
| 14 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 15 | A, B, J | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
B: 1 - 1164 (UniProt: Q49PH2)
| PDB | External Database | Details |
|---|---|---|
| Asn 6 | Asp 6 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 698346.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 285.9 | |
| All* | Total formula weight | 698632.2 |
