7AK0
Human MALT1(329-729) in complex with a chromane urea containing inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Mucosa-associated lymphoid tissue lymphoma translocation protein 1 | polymer | 404 | 45679.4 | 2 | UniProt (Q9UDY8) Pfam (PF00656) Pfam (PF18703) In PDB | Homo sapiens (Human) | MALT lymphoma-associated translocation,Paracaspase |
| 2 | A, B | 1-[4-[4-(aminomethyl)pyrazol-1-yl]-3-chloranyl-phenyl]-3-[(3~{R})-6-bromanyl-3,4-dihydro-2~{H}-chromen-3-yl]urea | non-polymer | 476.8 | 2 | Chemie (RJK) | |||
| 3 | water | water | 18.0 | 267 | Chemie (HOH) |
Sequence modifications
A, B: 329 - 728 (UniProt: Q9UDY8)
| PDB | External Database | Details |
|---|---|---|
| Gly 325 | - | expression tag |
| Pro 326 | - | expression tag |
| Gly 327 | - | expression tag |
| Ser 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91358.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 953.5 | |
| All* | Total formula weight | 92312.3 |
