7AI6
MutS in mismatch bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | DNA mismatch repair protein MutS | polymer | 853 | 95269.6 | 2 | UniProt (P23909) Pfam (PF01624) Pfam (PF05188) Pfam (PF05192) Pfam (PF05190) Pfam (PF00488) In PDB | Escherichia coli (strain K12) | |
| 2 | C | DNA (25-MER) | polymer | 25 | 7780.0 | 1 | synthetic construct | ||
| 3 | D | DNA (25-MER) | polymer | 25 | 7594.9 | 1 | synthetic construct | ||
| 4 | A | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
A, B: 1 - 853 (UniProt: P23909)
| PDB | External Database | Details |
|---|---|---|
| Ala 93 | Cys 93 | engineered mutation |
| Ser 235 | Cys 235 | engineered mutation |
| Ala 239 | Cys 239 | engineered mutation |
| Cys 246 | Asp 246 | engineered mutation |
| Ser 297 | Cys 297 | engineered mutation |
| Ser 569 | Cys 569 | engineered mutation |
| Val 711 | Cys 711 | engineered mutation |
| Arg 835 | Asp 835 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 205914.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 427.2 | |
| All* | Total formula weight | 206341.4 |
