Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A5 | Nuclear cap-binding protein subunit 1 | polymer | 790 | 91960.3 | 1 | UniProt (Q09161) Pfam (PF02854) Pfam (PF09088) Pfam (PF09090) In PDB | Homo sapiens (Human) | 80 kDa nuclear cap-binding protein,NCBP 80 kDa subunit |
| 2 | A2 | U6 snRNA-associated Sm-like protein LSm7 | polymer | 103 | 11617.4 | 1 | UniProt (Q9UK45) Pfam (PF01423) In PDB | Homo sapiens (Human) | |
| 3 | z | Splicing factor 3B subunit 6 | polymer | 125 | 14606.9 | 1 | UniProt (Q9Y3B4) Pfam (PF00076) In PDB | Homo sapiens (Human) | Pre-mRNA branch site protein p14,SF3b 14 kDa subunit,SF3B14a,Spliceosome-associated protein,14-kDa,Splicing factor 3b,subunit 6,14kDa |
| 4 | F | Splicing factor 3A subunit 2 | polymer | 464 | 49327.4 | 1 | UniProt (Q15428) Pfam (PF12874) Pfam (PF16835) In PDB | Homo sapiens (Human) | SF3a66,Spliceosome-associated protein 62,SAP 62 |
| 5 | D | U5 small nuclear ribonucleoprotein 40 kDa protein | polymer | 357 | 39359.5 | 1 | UniProt (Q96DI7) Pfam (PF00400) In PDB | Homo sapiens (Human) | U5-40K,38 kDa-splicing factor,Prp8-binding protein,hPRP8BP,U5 snRNP-specific 40 kDa protein,WD repeat-containing protein 57 |
| 6 | W | U2 small nuclear ribonucleoprotein A' | polymer | 255 | 28456.6 | 1 | UniProt (P09661) Pfam (PF14580) In PDB | Homo sapiens (Human) | U2 snRNP A' |
| 7 | B | U2 small nuclear ribonucleoprotein B'' | polymer | 225 | 25524.4 | 1 | UniProt (P08579) Pfam (PF00076) In PDB | Homo sapiens (Human) | U2 snRNP B'' |
| 8 | s | U5 small nuclear ribonucleoprotein 200 kDa helicase | polymer | 2136 | 244823.4 | 1 | UniProt (O75643) Pfam (PF21188) Pfam (PF18149) Pfam (PF00270) Pfam (PF00271) Pfam (PF02889) In PDB | Homo sapiens (Human) | Activating signal cointegrator 1 complex subunit 3-like 1,BRR2 homolog,U5 snRNP-specific 200 kDa protein,U5-200KD |
| 9 | Q | Protein BUD31 homolog | polymer | 144 | 17032.8 | 1 | UniProt (P41223) Pfam (PF01125) In PDB | Homo sapiens (Human) | Protein EDG-2,Protein G10 homolog |
| 10 | A1 | Nuclear cap-binding protein subunit 2 | polymer | 156 | 18028.1 | 1 | UniProt (P52298) Pfam (PF00076) In PDB | Homo sapiens (Human) | 20 kDa nuclear cap-binding protein,Cell proliferation-inducing gene 55 protein,NCBP 20 kDa subunit,CBP20,NCBP-interacting protein 1,NIP1 |
| 11 | 5 | U5 snRNA | polymer | 116 | 36908.7 | 1 | GenBank (36515) | Homo sapiens (Human) | |
| 12 | L | Cell division cycle 5-like protein | polymer | 802 | 92406.9 | 1 | UniProt (Q99459) Pfam (PF13921) Pfam (PF11831) In PDB | Homo sapiens (Human) | Cdc5-like protein,Pombe cdc5-related protein |
| 13 | R | Spliceosome-associated protein CWC15 homolog | polymer | 229 | 26674.4 | 1 | UniProt (Q9P013) Pfam (PF04889) In PDB | Homo sapiens (Human) | |
| 14 | V | U6 snRNA-associated Sm-like protein LSm2 | polymer | 95 | 10847.5 | 1 | UniProt (Q9Y333) Pfam (PF01423) In PDB | Homo sapiens (Human) | Protein G7b,Small nuclear ribonuclear protein D homolog,snRNP core Sm-like protein Sm-x5 |
| 15 | 9 | U6 snRNA-associated Sm-like protein LSm3 | polymer | 102 | 11859.4 | 1 | UniProt (P62310) Pfam (PF01423) In PDB | Homo sapiens (Human) | |
| 16 | C | U6 snRNA-associated Sm-like protein LSm4 | polymer | 139 | 15375.8 | 1 | UniProt (Q9Y4Z0) Pfam (PF01423) In PDB | Homo sapiens (Human) | Glycine-rich protein,GRP |
| 17 | H | U6 snRNA-associated Sm-like protein LSm5 | polymer | 91 | 9945.4 | 1 | UniProt (Q9Y4Y9) Pfam (PF01423) In PDB | Homo sapiens (Human) | |
| 18 | J | U6 snRNA-associated Sm-like protein LSm6 | polymer | 80 | 9139.6 | 1 | UniProt (P62312) Pfam (PF01423) In PDB | Homo sapiens (Human) | |
| 19 | 2 | U2 snRNA | polymer | 188 | 60186.4 | 1 | GenBank (36516) | Homo sapiens | |
| 20 | A3 | U6 snRNA-associated Sm-like protein LSm8 | polymer | 96 | 10410.6 | 1 | UniProt (O95777) Pfam (PF01423) In PDB | Homo sapiens (Human) | |
| 21 | K | Microfibrillar-associated protein 1 | polymer | 439 | 52050.5 | 1 | UniProt (P55081) Pfam (PF06991) In PDB | Homo sapiens (Human) | |
| 22 | y | PHD finger-like domain-containing protein 5A | polymer | 110 | 12427.5 | 1 | UniProt (Q7RTV0) Pfam (PF03660) In PDB | Homo sapiens (Human) | PHD finger-like domain protein 5A,Splicing factor 3B-associated 14 kDa protein,SF3b14b |
| 23 | G | Pleiotropic regulator 1 | polymer | 514 | 57280.8 | 1 | UniProt (O43660) Pfam (PF00400) In PDB | Homo sapiens (Human) | |
| 24 | Z | MINX M3 pre-mRNA | polymer | 230 | 73712.4 | 1 | synthetic construct | ||
| 25 | A | Pre-mRNA-processing-splicing factor 8 | polymer | 2335 | 273974.3 | 1 | UniProt (Q6P2Q9) Pfam (PF10597) Pfam (PF10596) Pfam (PF12134) Pfam (PF01398) Pfam (PF08084) Pfam (PF08082) Pfam (PF08083) Pfam (PF10598) In PDB | Homo sapiens (Human) | 220 kDa U5 snRNP-specific protein,PRP8 homolog,Splicing factor Prp8,p220 |
| 26 | I | Pre-mRNA-splicing factor 38A | polymer | 312 | 37563.9 | 1 | UniProt (Q8NAV1) Pfam (PF03371) Pfam (PF12871) In PDB | Homo sapiens (Human) | |
| 27 | P | Pre-mRNA-splicing factor RBM22 | polymer | 420 | 46959.6 | 1 | UniProt (Q9NW64) Pfam (PF21369) Pfam (PF00076) In PDB | Homo sapiens (Human) | RNA-binding motif protein 22,Zinc finger CCCH domain-containing protein 16 |
| 28 | p | Splicing factor 3A subunit 1 | polymer | 793 | 88991.1 | 1 | UniProt (Q15459) Pfam (PF01805) Pfam (PF12230) Pfam (PF00240) In PDB | Homo sapiens (Human) | SF3a120,Spliceosome-associated protein 114,SAP 114 |
| 29 | 4 | Splicing factor 3A subunit 3 | polymer | 501 | 58934.8 | 1 | UniProt (Q12874) Pfam (PF12108) Pfam (PF16837) Pfam (PF13297) Pfam (PF11931) In PDB | Homo sapiens (Human) | SF3a60,Spliceosome-associated protein 61,SAP 61 |
| 30 | A4 | Transcription elongation regulator 1 | polymer | 1098 | 124083.0 | 1 | UniProt (O14776) Pfam (PF00397) Pfam (PF01846) In PDB | Homo sapiens (Human) | TATA box-binding protein-associated factor 2S,Transcription factor CA150 |
| 31 | u | Splicing factor 3B subunit 1 | polymer | 1304 | 146024.9 | 1 | UniProt (O75533) Pfam (PF08920) In PDB | Homo sapiens (Human) | Pre-mRNA-splicing factor SF3b 155 kDa subunit,SF3b155,Spliceosome-associated protein 155,SAP 155 |
| 32 | T | Splicing factor 3B subunit 2 | polymer | 895 | 100377.8 | 1 | UniProt (Q13435) Pfam (PF02037) Pfam (PF04037) Pfam (PF04046) In PDB | Homo sapiens (Human) | Pre-mRNA-splicing factor SF3b 145 kDa subunit,SF3b145,Spliceosome-associated protein 145,SAP 145 |
| 33 | E | Splicing factor 3B subunit 3 | polymer | 1217 | 135718.8 | 1 | UniProt (Q15393) Pfam (PF10433) Pfam (PF03178) In PDB | Homo sapiens (Human) | Pre-mRNA-splicing factor SF3b 130 kDa subunit,SF3b130,STAF130,Spliceosome-associated protein 130,SAP 130 |
| 34 | w | Splicing factor 3B subunit 4 | polymer | 424 | 44436.6 | 1 | UniProt (Q15427) Pfam (PF00076) In PDB | Homo sapiens (Human) | Pre-mRNA-splicing factor SF3b 49 kDa subunit,Spliceosome-associated protein 49,SAP 49 |
| 35 | x | Splicing factor 3B subunit 5 | polymer | 86 | 10149.4 | 1 | UniProt (Q9BWJ5) Pfam (PF07189) In PDB | Homo sapiens (Human) | SF3b5,Pre-mRNA-splicing factor SF3b 10 kDa subunit |
| 36 | v | SNW domain-containing protein 1 | polymer | 536 | 61610.7 | 1 | UniProt (Q13573) Pfam (PF02731) In PDB | Homo sapiens (Human) | Nuclear protein SkiP,Nuclear receptor coactivator NCoA-62,Ski-interacting protein |
| 37 | 0 | Smad nuclear-interacting protein 1 | polymer | 396 | 45880.7 | 1 | UniProt (Q8TAD8) Pfam (PF00498) In PDB | Homo sapiens (Human) | FHA domain-containing protein SNIP1 |
| 38 | N | Zinc finger matrin-type protein 2 | polymer | 199 | 23664.0 | 1 | UniProt (Q96NC0) Pfam (PF12171) In PDB | Homo sapiens (Human) | |
| 39 | r | 116 kDa U5 small nuclear ribonucleoprotein component | polymer | 972 | 109560.6 | 1 | UniProt (Q15029) Pfam (PF16004) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) In PDB | Homo sapiens (Human) | Elongation factor Tu GTP-binding domain-containing protein 2,SNU114 homolog,hSNU114,U5 snRNP-specific protein,116 kDa,U5-116 kDa |
| 40 | Y | Serine/arginine repetitive matrix protein 1 | polymer | 904 | 102600.5 | 1 | UniProt (Q8IYB3) Pfam (PF01480) In PDB | Homo sapiens (Human) | SR-related nuclear matrix protein of 160 kDa,SRm160,Ser/Arg-related nuclear matrix protein |
| 41 | 6 | U6 snRNA | polymer | 106 | 34098.3 | 1 | Homo sapiens | ||
| 42 | A6 | Serine/arginine-rich splicing factor 1 | polymer | 248 | 27798.8 | 1 | UniProt (Q07955) Pfam (PF00076) In PDB | Homo sapiens (Human) | Alternative-splicing factor 1,ASF-1,Splicing factor,arginine/serine-rich 1,pre-mRNA-splicing factor SF2,P33 subunit |
| 43 | h, a | Small nuclear ribonucleoprotein Sm D2 | polymer | 118 | 13551.9 | 2 | UniProt (P62316) Pfam (PF01423) In PDB | Homo sapiens (Human) | Sm-D2,snRNP core protein D2 |
| 44 | i, b | Small nuclear ribonucleoprotein F | polymer | 86 | 9734.2 | 2 | UniProt (P62306) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-F,Sm protein F,SmF |
| 45 | m, f | Small nuclear ribonucleoprotein-associated proteins B and B' | polymer | 240 | 24642.1 | 2 | UniProt (P14678) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-B,Sm protein B/B',SmB/B' |
| 46 | l, e | Small nuclear ribonucleoprotein Sm D3 | polymer | 126 | 13940.3 | 2 | UniProt (P62318) Pfam (PF01423) In PDB | Homo sapiens (Human) | Sm-D3,snRNP core protein D3 |
| 47 | k, d | Small nuclear ribonucleoprotein G | polymer | 76 | 8508.1 | 2 | UniProt (P62308) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-G,Sm protein G,SmG |
| 48 | j, c | Small nuclear ribonucleoprotein E | polymer | 92 | 10817.6 | 2 | UniProt (P62304) Pfam (PF01423) In PDB | Homo sapiens (Human) | snRNP-E,Sm protein E,SmE |
| 49 | n, g | Small nuclear ribonucleoprotein Sm D1 | polymer | 119 | 13310.7 | 2 | UniProt (P62314) Pfam (PF01423) In PDB | Homo sapiens (Human) | Sm-D1,Sm-D autoantigen,snRNP core protein D1 |
| 50 | q | Ubiquitin-like protein 5 | polymer | 73 | 8560.9 | 1 | UniProt (Q9BZL1) Pfam (PF00240) In PDB | Homo sapiens (Human) | |
| 51 | X | WW domain-binding protein 11 | polymer | 641 | 70098.6 | 1 | UniProt (Q9Y2W2) Pfam (PF09429) In PDB | Homo sapiens (Human) | WBP-11,Npw38-binding protein,NpwBP,SH3 domain-binding protein SNP70,Splicing factor that interacts with PQBP-1 and PP1 |
| 52 | A | INOSITOL HEXAKISPHOSPHATE | non-polymer | 660.0 | 1 | Chemie (IHP) | |||
| 53 | r | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) | |||
| 54 | r | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 55 | A6 | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE | non-polymer | 803.4 | 1 | Chemie (GTG) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 58 |
| Total formula weight | 2760059.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2011.0 | |
| All* | Total formula weight | 2762070.8 |
