6YZH

Crystal structure of P8C9 bound to CK2alpha

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Casein kinase II subunit alpha	polymer	398	46719.6	1	UniProt (P68400) Pfam (PF00069) In PDB	Homo sapiens (human)	CK II alpha
2	D	P8C9	polymer	10	1141.4	1		Homo sapiens (Human)
3	A	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
5	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
6	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7		water	water		18.0	354	Chemie (HOH)

Sequence modifications

A: 3 - 329 (UniProt: P68400)

PDB	External Database	Details
Met -46	-	initiating methionine
Asn -45	-	expression tag
Thr -44	-	expression tag
Ile -43	-	expression tag
His -42	-	expression tag
His -41	-	expression tag
His -40	-	expression tag
His -39	-	expression tag
His -38	-	expression tag
His -37	-	expression tag
Asn -36	-	expression tag
Thr -35	-	expression tag
Ser -34	-	expression tag
Gly -33	-	expression tag
Ser -32	-	expression tag
Gly -31	-	expression tag
Gly -30	-	expression tag
Gly -29	-	expression tag
Gly -28	-	expression tag
Gly -27	-	expression tag
Arg -26	-	expression tag
Leu -25	-	expression tag
Val -24	-	expression tag
Pro -23	-	expression tag
Arg -22	-	expression tag
Gly -21	-	expression tag
Ser -20	-	expression tag
Met -19	-	expression tag
Ser -18	-	expression tag
Glu -17	-	expression tag
Asn -16	-	expression tag
Leu -15	-	expression tag
Tyr -14	-	expression tag
Phe -13	-	expression tag
Gln -12	-	expression tag
Gly -11	-	expression tag
Ser -10	-	expression tag
Met -9	-	expression tag
Asp -8	-	expression tag
Ile -7	-	expression tag
Glu -6	-	expression tag
Phe -5	-	expression tag
Gly -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Glu -1	-	expression tag
Gly 0	-	expression tag
Ser 1	-	expression tag
Glu 2	-	expression tag
Ser 21	Arg 21	conflict
Glu 330	-	expression tag
Asn 331	-	expression tag
Leu 332	-	expression tag
Tyr 333	-	expression tag
Phe 334	-	expression tag
Gln 335	-	expression tag
Gly 336	-	expression tag
Ser 337	-	expression tag
Ser 338	-	expression tag
Gly 339	-	expression tag
Ser 340	-	expression tag
Gly 341	-	expression tag
Ser 342	-	expression tag
Gly 343	-	expression tag
Ser 344	-	expression tag
Ser 345	-	expression tag
His 346	-	expression tag
His 347	-	expression tag
His 348	-	expression tag
His 349	-	expression tag
His 350	-	expression tag
His 351	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47861.0
Non-Polymers*	Number of molecules	5
	Total formula weight	590.9
All*	Total formula weight	48451.9

*Water molecules are not included.