6YQ2
14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-129
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 14-3-3 protein sigma | polymer | 236 | 26558.9 | 1 | UniProt (P31947) Pfam (PF00244) In PDB | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | P | p65pS45 | polymer | 13 | 1412.4 | 1 | UniProt (by SIFTS) (Q04206) In PDB | Homo sapiens | |
| 3 | A | 4-[(2~{R},6~{S})-2,6-dimethylmorpholin-4-yl]sulfonylbenzaldehyde | non-polymer | 283.3 | 1 | Chemie (P7T) | |||
| 4 | water | water | 18.0 | 285 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27971.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 283.3 | |
| All* | Total formula weight | 28254.7 |
