6YMQ

TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4)

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Single-chain variable 4	polymer	245	26245.0	6		Homo sapiens (Human)
2	G, H, I, J, K...	Triggering receptor expressed on myeloid cells 2	polymer	125	14067.8	6	UniProt (Q9NZC2) Pfam (PF07686) In PDB	Homo sapiens (human)	TREM-2,Triggering receptor expressed on monocytes 2
3	G, H, I, J, K...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
4	J	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	1	Chemie (MPD)
5		water	water		18.0	13	Chemie (HOH)

Sequence modifications

G, H, I, J, K, D000: 19 - 131 (UniProt: Q9NZC2)

PDB	External Database	Details
Glu 16	-	expression tag
Thr 17	-	expression tag
Gly 18	-	expression tag
Gly 132	-	expression tag
Thr 133	-	expression tag
Lys 134	-	expression tag
His 135	-	expression tag
His 136	-	expression tag
His 137	-	expression tag
His 138	-	expression tag
His 139	-	expression tag
His 140	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	241876.9
Non-Polymers*	Number of molecules	7
	Total formula weight	1445.4
All*	Total formula weight	243322.3

*Water molecules are not included.