6YL4
Soluble epoxide hydrolase in complex with 3-((R)-3-(1-hydroxyureido)but-1-yn-1-yl)-N-((S)-3-phenyl-3-(4-trifluoromethoxy)phenyl)propyl)benzamide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bifunctional epoxide hydrolase 2 | polymer | 346 | 39648.5 | 1 | UniProt (P34913) Pfam (PF00561) In PDB | Homo sapiens (Human) | |
2 | A | 3-[(3~{R})-3-[aminocarbonyl(oxidanyl)amino]but-1-ynyl]-~{N}-[(3~{S})-3-phenyl-3-[4-(trifluoromethyloxy)phenyl]propyl]benzamide | non-polymer | 525.5 | 1 | Chemie (OWW) | |||
3 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 222 - 555 (UniProt: P34913)
PDB | External Database | Details |
---|---|---|
Met 219 | - | initiating methionine |
Ala 220 | - | expression tag |
Ser 221 | - | expression tag |
Leu 556 | - | expression tag |
Leu 557 | - | expression tag |
Glu 558 | - | expression tag |
His 559 | - | expression tag |
His 560 | - | expression tag |
His 561 | - | expression tag |
His 562 | - | expression tag |
His 563 | - | expression tag |
His 564 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 39648.5 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 525.5 | |
All* | Total formula weight | 40174.1 |