6XVG
Human Sirt6 3-318 in complex with ADP-ribose and the activator MDL-801
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | NAD-dependent protein deacetylase sirtuin-6 | polymer | 316 | 35003.1 | 6 | UniProt (Q8N6T7) Pfam (PF02146) In PDB | Homo sapiens (Human) | Regulatory protein SIR2 homolog 6,SIR2-like protein 6 |
| 2 | D, A, E, B, F... | [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE | non-polymer | 559.3 | 6 | Chemie (AR6) | |||
| 3 | D, A, E, B, F... | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | D, A, E, B, C | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 5 | D, A, E, B, F... | 5-[[3,5-bis(chloranyl)phenyl]sulfonylamino]-2-[(5-bromanyl-4-fluoranyl-2-methyl-phenyl)sulfamoyl]benzoic acid | non-polymer | 612.3 | 6 | Chemie (8L9) | |||
| 6 | C, D, A, E, B | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 7 | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 210018.6 | |
| Non-Polymers* | Number of molecules | 39 |
| Total formula weight | 9407.6 | |
| All* | Total formula weight | 219426.2 |
