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6XV6

Human Sirt6 3-318 in complex with ADP-ribose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...NAD-dependent protein deacetylase sirtuin-6polymer31635003.16UniProt (Q8N6T7)
Pfam (PF02146)
In PDB
Homo sapiens (Human)Regulatory protein SIR2 homolog 6,SIR2-like protein 6
2D, A, B, E, F...[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATEnon-polymer559.36Chemie (AR6)
3C, D, A, B, E...ZINC IONnon-polymer65.46Chemie (ZN)
4C, D, A, B, E...NICOTINAMIDEnon-polymer122.16Chemie (NCA)
5D, A, B, E, FGLYCEROLnon-polymer92.18Chemie (GOL)
6F, C, D, A, E...SULFATE IONnon-polymer96.122Chemie (SO4)
7waterwater18.0504Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight210018.6
Non-Polymers*Number of molecules48
Total formula weight7331.2
All*Total formula weight217349.9
*Water molecules are not included.

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PDB entries from 2024-05-15

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