6XBU

polymerase domain of polymerase-theta

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA polymerase theta	polymer	652	72591.7	1	UniProt (O75417) Pfam (PF00476) In PDB	Homo sapiens (Human)	DNA polymerase eta,DNA polymerase eta,DNA polymerase eta,DNA polymerase eta,DNA polymerase eta,DNA polymerase eta
2	F	DNA (5'-D(P*GP*TP*CP*AP*TP*TP*G)-3')	polymer	13	3998.6	1		synthetic construct
3	E	RNA (5'-R(P*CP*CP*AP*AP*UP*GP*A)-3')	polymer	17	5401.3	1		synthetic construct
4	A	2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE	non-polymer		491.2	1	Chemie (DG3)

Sequence modifications

A: 1819 - 1860 (UniProt: O75417)
A: 1896 - 1917 (UniProt: O75417)

PDB	External Database	Details
Gly 1861	-	linker
Ser 1894	-	linker
Gly 1895	-	linker

A: 1935 - 2170 (UniProt: O75417)

PDB	External Database	Details
Gly 1930	-	linker
Gly 1931	-	linker
Ser 1932	-	linker
Gly 1933	-	linker
Gly 1934	-	linker

A: 2176 - 2260 (UniProt: O75417)

PDB	External Database	Details
Gly 2171	-	linker
Gly 2172	-	linker
Ser 2173	-	linker
Gly 2174	-	linker
Gly 2175	-	linker

A: 2307 - 2512 (UniProt: O75417)

PDB	External Database	Details
Gly 2303	-	linker
Gly 2304	-	linker
Ser 2305	-	linker
Gly 2306	-	linker
Asp 2378	Leu 2378	conflict

A: 2527 - 2590 (UniProt: O75417)

PDB	External Database	Details
Gly 2522	-	linker
Gly 2523	-	linker
Ser 2524	-	linker
Gly 2525	-	linker
Gly 2526	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	81991.6
Non-Polymers*	Number of molecules	1
	Total formula weight	491.2
All*	Total formula weight	82482.8

*Water molecules are not included.