6X8L

Caspase-7 in complex with elongated ketomethylene inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Caspase-7	polymer	198	22189.2	2	UniProt (P55210) Pfam (PF00656) In PDB	Homo sapiens (Human)	CASP-7,Apoptotic protease Mch-3,CMH-1,ICE-like apoptotic protease 3,ICE-LAP3
2	C, D	Caspase-7	polymer	113	13223.8	2	UniProt (P55210) Pfam (PF00656) In PDB	Homo sapiens (Human)	CASP-7,Apoptotic protease Mch-3,CMH-1,ICE-like apoptotic protease 3,ICE-LAP3
3	E, F	ketomethylene inhibitor	polymer	8	773.8	2		synthetic construct
4		water	water		18.0	61	Chemie (HOH)

Sequence modifications

C, D: 199 - 303 (UniProt: P55210)

PDB	External Database	Details
Leu 304	-	expression tag
Glu 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag
His 311	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	72373.6
All*	Total formula weight	72373.6

*Water molecules are not included.