6X87

CryoEM structure of the Plasmodium berghei circumsporozoite protein in complex with inhibitory mouse antibody 3D11.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	K, M, I, G, E...	3D11 Fab heavy chain	polymer	217	22830.5	7		Mus musculus (Mouse)
2	L, N, J, H, F...	3D11 Fab kappa chain	polymer	221	24191.0	7		Mus musculus (Mouse)
3	X	Circumsporozoite protein	polymer	334	36397.0	1	UniProt (D1L8V5) Pfam (PF00090) UniProt (by SIFTS) (P06915) In PDB	Plasmodium berghei

Sequence modifications

X: -67 - 225 (UniProt: D1L8V5)

PDB	External Database	Details
Glu -101	-	expression tag
Phe -100	-	expression tag
Ala -99	-	expression tag
Thr -98	-	expression tag
Met -97	-	expression tag
Gly -96	-	expression tag
Ile -95	-	expression tag
Leu -94	-	expression tag
Pro -93	-	expression tag
Ser -92	-	expression tag
Pro -91	-	expression tag
Gly -90	-	expression tag
Met -89	-	expression tag
Pro -88	-	expression tag
Ala -87	-	expression tag
Leu -86	-	expression tag
Leu -85	-	expression tag
Ser -84	-	expression tag
Leu -83	-	expression tag
Val -82	-	expression tag
Ser -81	-	expression tag
Leu -80	-	expression tag
Leu -79	-	expression tag
Ser -78	-	expression tag
Val -77	-	expression tag
Leu -76	-	expression tag
Leu -75	-	expression tag
Met -74	-	expression tag
Gly -73	-	expression tag
Cys -72	-	expression tag
Val -71	-	expression tag
Ala -70	-	expression tag
Gln -69	-	expression tag
Gln -68	-	expression tag
Pro 30	Unk 114	conflict
Gln 187	Asn 271	conflict
Pro 226	-	expression tag
His 227	-	expression tag
His 228	-	expression tag
His 229	-	expression tag
His 230	-	expression tag
His 231	-	expression tag
His 232	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	15
	Total formula weight	365547.5
All*	Total formula weight	365547.5

*Water molecules are not included.