6W5X
Crystal structure of human polymerase eta complexed with N7-benzylguanine and dCTP*
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA polymerase eta | polymer | 432 | 48325.4 | 1 | UniProt (Q9Y253) Pfam (PF00817) Pfam (PF21704) Pfam (PF11799) In PDB | Homo sapiens (Human) | RAD30 homolog A,Xeroderma pigmentosum variant type protein |
| 2 | T | DNA (5'-D(*CP*AP*TP*(DRG)P*CP*TP*CP*AP*CP*AP*CP*T)-3') | polymer | 12 | 3691.5 | 1 | Homo sapiens | ||
| 3 | P | DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3') | polymer | 8 | 2506.7 | 1 | Homo sapiens | ||
| 4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | A | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine | non-polymer | 466.2 | 1 | Chemie (0KX) | |||
| 6 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 7 | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 54523.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 668.1 | |
| All* | Total formula weight | 55191.7 |
