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6UZU

Carbonic Anhydrase IX-mimic In Complex WITH U-CH3

Replaces:  5JN1
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ACarbonic anhydrase 2polymer25728844.51UniProt (P00918)
Pfam (PF00194)
In PDB
Homo sapiens (Human)Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II
2AZINC IONnon-polymer65.41Chemie (ZN)
3A4-{[(3,5-dimethylphenyl)carbamoyl]amino}benzene-1-sulfonamidenon-polymer319.41Chemie (6LU)
4ADIMETHYL SULFOXIDEnon-polymer78.12Chemie (DMS)
5waterwater18.0184Chemie (HOH)
Sequence modifications
A: 4 - 261 (UniProt: P00918)
PDBExternal DatabaseDetails
Ser 65Ala 65engineered mutation
Gln 67Asn 67engineered mutation
Thr 69Glu 69engineered mutation
Leu 91Ile 91engineered mutation
Val 131Phe 130engineered mutation
Glu 170Lys 169engineered mutation
Ala 204Leu 203engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight28844.5
Non-Polymers*Number of molecules4
Total formula weight541.1
All*Total formula weight29385.5
*Water molecules are not included.

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PDB entries from 2024-05-15

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