6UK3
Crystal Structure of S-adenosyl-L-homocysteine hydrolase from Acanthamoeba castellanii with bound NAD and Adenosine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Adenosylhomocysteinase | polymer | 485 | 54174.9 | 4 | UniProt (L8H6B5) Pfam (PF05221) Pfam (PF00670) In PDB | Acanthamoeba castellanii str. Neff | |
2 | A, B, C, D | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
3 | A, B, C, D | ADENOSINE | non-polymer | 267.2 | 4 | Chemie (ADN) | |||
4 | D, A, B, C | FORMIC ACID | non-polymer | 46.0 | 9 | Chemie (FMT) | |||
5 | D, A, B, C | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
6 | A | OXAMIC ACID | non-polymer | 89.0 | 1 | Chemie (OXM) | |||
7 | D, B, C | ACETATE ION | non-polymer | 59.0 | 5 | Chemie (ACT) | |||
8 | water | water | 18.0 | 2329 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 477 (UniProt: L8H6B5)
PDB | External Database | Details |
---|---|---|
Met -7 | - | initiating methionine |
Ala -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
His -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 216699.7 | |
Non-Polymers* | Number of molecules | 27 |
Total formula weight | 4677.6 | |
All* | Total formula weight | 221377.3 |