6UJK

Crystal Structure of a Probable short-chain type dehydrogenase/reductase (Rv1144) from Mycobacterium tuberculosis with bound NAD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Uncharacterized oxidoreductase Rv1144	polymer	258	26845.9	2	UniProt (P9WGQ7) Pfam (PF00106) In PDB	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	MytuD.00554.a.B1
2	A, B	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	A, B	1,2-ETHANEDIOL	non-polymer		62.1	7	Chemie (EDO)
4	A	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
5		water	water		18.0	519	Chemie (HOH)

Sequence modifications

A, B: 1 - 250 (UniProt: P9WGQ7)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53691.8
Non-Polymers*	Number of molecules	10
	Total formula weight	1883.5
All*	Total formula weight	55575.2

*Water molecules are not included.