6U3V

Crystal structure of human alpha/epsilon-COP of the COPI vesicular coat bound to alpha-COP STM1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Coatomer subunit epsilon	polymer	322	36139.7	2	UniProt (O14579) Pfam (PF04733) In PDB	Homo sapiens (Human)	Epsilon-coat protein,Epsilon-COP
2	B, D	Coatomer subunit alpha	polymer	356	39975.1	2	UniProt (P53621) Pfam (PF06957) In PDB	Homo sapiens (Human)	Alpha-coat protein,Alpha-COP,HEP-COP,HEPCOP

Sequence modifications

A, C: 1 - 308 (UniProt: O14579)

PDB	External Database	Details
Met -13	-	expression tag
Gly -12	-	expression tag
Ser -11	-	expression tag
Ser -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
Ser -3	-	expression tag
Gln -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag

B, D: 835 - 1224 (UniProt: P53621)

PDB	External Database	Details
Met 834	-	initiating methionine
-	Asp 854	deletion
-	Glu 855	deletion
-	Asp 856	deletion
-	Gly 857	deletion
-	Phe 858	deletion
-	Val 859	deletion
-	Glu 860	deletion
-	Ala 861	deletion
-	Thr 862	deletion
-	Glu 863	deletion
-	Gly 864	deletion
-	Leu 865	deletion
-	Gly 866	deletion
-	Asp 867	deletion
-	Asp 868	deletion
-	Ala 869	deletion
-	Leu 870	deletion
-	Gly 871	deletion
-	Lys 872	deletion
-	Gly 873	deletion
-	Gln 874	deletion
-	Glu 875	deletion
-	Glu 876	deletion
-	Gly 877	deletion
-	Gly 878	deletion
-	Gly 879	deletion
-	Trp 880	deletion
-	Asp 881	deletion
-	Val 882	deletion
-	Glu 883	deletion
-	Glu 884	deletion
-	Asp 885	deletion
-	Leu 886	deletion
-	Glu 887	deletion
-	Leu 888	deletion

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	152229.5
All*	Total formula weight	152229.5

*Water molecules are not included.