6TWV

Crystal structure of the haemagglutinin mutant (Gln226Leu) from an H10N7 seal influenza virus isolated in Germany with human receptor analogue, 6'SLN

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, E, K, A, G...	Hemagglutinin HA1	polymer	325	35484.1	6	UniProt (A0A0A7HR51) Pfam (PF00509) In PDB	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
2	D, F, L, B, H...	Hemagglutinin HA2	polymer	177	20313.4	6	UniProt (A0A0A7HR51) Pfam (PF00509) In PDB	Influenza A virus (A/harbour seal/Germany/1/2014(H10N7))
3	M, O, P, Q	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		674.6	4	In PDB BIRD (PRD_900046) GlyTouCan (G73578JC)		6'-sialyl-N-acetyllactosamine
4	N	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose	branched		471.4	1	In PDB GlyTouCan (G63069TR)
5	C, B	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
6	G, H, J, C, D...	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	10	Chemie (NAG)
7		water	water		18.0	167	Chemie (HOH)

Sequence modifications

C, E, K, A, G, I: 1 - 323 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Asp -1	-	expression tag
Pro 0	-	expression tag

D, F, L, B, H, J: 1 - 176 (UniProt: A0A0A7HR51)

PDB	External Database	Details
Lys 177	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	334785.0
Branched	Number of molecules	5
	Total formula weight	3169.8
Non-Polymers*	Number of molecules	12
	Total formula weight	2292.2
All*	Total formula weight	340247.1

*Water molecules are not included.