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6T5P

Human Carbonic anhydrase XII bound by 3,5-Di-tert-butylbenzenesulfonamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DCarbonic anhydrase 12polymer26329917.34UniProt (O43570)
Pfam (PF00194)
In PDB
Homo sapiens (Human)Carbonate dehydratase XII,Carbonic anhydrase XII,CA-XII,Tumor antigen HOM-RCC-3.1.3
2A, B, C, DZINC IONnon-polymer65.44Chemie (ZN)
3A, B, C, D3,5-di~{tert}-butylbenzenesulfonamidenon-polymer269.44Chemie (VD8)
4B, C, D1,2-ETHANEDIOLnon-polymer62.16Chemie (EDO)
5waterwater18.0915Chemie (HOH)
Sequence modifications
A, B, C, D: 2 - 263 (UniProt: O43570)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight119669.3
Non-Polymers*Number of molecules14
Total formula weight1711.7
All*Total formula weight121380.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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