6RWM

SIVrcm intasome in complex with bictegravir

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, F...	Pol protein	polymer	290	32732.2	12	UniProt (E1ANT8) Pfam (PF02022) Pfam (PF00665) Pfam (PF00552) In PDB	Simian immunodeficiency virus
2	T, W	DNA (5'-D(P*GP*CP*TP*AP*AP*GP*AP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*CP*CP*A)-3')	polymer	30	9224.0	2		Simian immunodeficiency virus
3	S, Q	DNA (5'-D(*AP*AP*CP*TP*GP*GP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*TP*CP*TP*TP*AP*GP*C)-3')	polymer	33	10134.5	2		Simian immunodeficiency virus
4	J, K, E, A, B...	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
5	I, A	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	I, A	Bictegravir	non-polymer		449.4	2	Chemie (KLQ)
7	I, A	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
8		water	water		18.0	108	Chemie (HOH)

Sequence modifications

A, B, C, D, F, M, I, J, K, L, N, E: 1 - 289 (UniProt: E1ANT8)

PDB	External Database	Details
Gly 0	-	expression tag
Asp 119	Ala 853	conflict

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	431503.3
Non-Polymers*	Number of molecules	16
	Total formula weight	1590.2
All*	Total formula weight	433093.4

*Water molecules are not included.