6RQW
X-ray crystal structure of perdeuterated (D) small monoclinic unit cell CA IX SV.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Carbonic anhydrase 9 | polymer | 256 | 28092.6 | 1 | UniProt (Q16790) Pfam (PF00194) In PDB | Homo sapiens (Human) | Carbonate dehydratase IX,Carbonic anhydrase IX,CAIX,Membrane antigen MN,P54/58N,Renal cell carcinoma-associated antigen G250,RCC-associated antigen G250,pMW1 |
| 2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | A | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A: 140 - 395 (UniProt: Q16790)
| PDB | External Database | Details |
|---|---|---|
| Ser 174 | Cys 174 | engineered mutation |
| Ser 183 | Leu 183 | engineered mutation |
| Lys 213 | Ala 213 | engineered mutation |
| Lys 258 | Ala 258 | engineered mutation |
| Tyr 259 | Phe 259 | engineered mutation |
| Ser 350 | Met 350 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28092.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 111.4 | |
| All* | Total formula weight | 28204.0 |
