6PDJ
Tyrosine-protein kinase LCK bound to Compound 11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tyrosine-protein kinase Lck | polymer | 288 | 33392.0 | 1 | UniProt (P06239) Pfam (PF07714) In PDB | Homo sapiens (Human) | Leukocyte C-terminal Src kinase,LSK,Lymphocyte cell-specific protein-tyrosine kinase,Protein YT16,Proto-oncogene Lck,T cell-specific protein-tyrosine kinase,p56-LCK |
| 2 | A | N-{4-[(6-methoxypyrazolo[1,5-a]pyridine-3-carbonyl)amino]-3-methylphenyl}-1-methyl-1H-indazole-3-carboxamide | non-polymer | 454.5 | 1 | Chemie (ODJ) | |||
| 3 | A | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID | non-polymer | 221.3 | 1 | Chemie (CXS) | |||
| 4 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | A | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 6 | water | water | 18.0 | 291 | Chemie (HOH) |
Sequence modifications
A: 225 - 509 (UniProt: P06239)
| PDB | External Database | Details |
|---|---|---|
| Gly 222 | - | expression tag |
| His 223 | - | expression tag |
| Met 224 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33392.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 926.6 | |
| All* | Total formula weight | 34318.6 |
