6P3R

crystal structure of human Fab H5.31 in complex with influenza A H5N1 Vietnam hemagglutinin head domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	human Fab H5.31 heavy chain	polymer	230	24659.7	2		Homo sapiens
2	B, D	Human Fab H5.31 light chain	polymer	215	23396.0	2		Homo sapiens
3	E, L	Hemagglutinin	polymer	219	25162.4	2	UniProt (Q1KHK2) Pfam (PF00509) In PDB	Influenza A virus (A/chicken/Vietnam/32/2004(H5N1))
4	F	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1
5	G	N-acetyl-alpha-neuraminic acid-(2-6)-alpha-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1567.4	1
6	H	N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-D-fructofuranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1567.4	1
7	B, D, L	PHOSPHATE ION	non-polymer		95.0	3	Chemie (PO4)
8	C, E, L	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
9		water	water		18.0	42	Chemie (HOH)

Sequence modifications

E, L: 58 - 268 (UniProt: Q1KHK2)

PDB	External Database	Details
Ala 269	-	expression tag
Ala 270	-	expression tag
His 271	-	expression tag
His 272	-	expression tag
His 273	-	expression tag
His 274	-	expression tag
His 275	-	expression tag
His 276	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	146436.2
Branched	Number of molecules	3
	Total formula weight	3559.2
Non-Polymers*	Number of molecules	6
	Total formula weight	948.5
All*	Total formula weight	150943.9

*Water molecules are not included.