6OZ2
Crystal structure of the broadly neutralizing antibody N49P6 Fab in complex with HIV-1 Clade A/E strain 93TH057 gp120 core.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G | clade A/E 93TH057 HIV-1 gp120 core | polymer | 355 | 39356.6 | 1 | UniProt (A0A0M3KKW9) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | H | N49P6 antibody Fab heavy chain | polymer | 229 | 24885.9 | 1 | Homo sapiens | ||
3 | L | N49P6 antibody Fab light chain | polymer | 205 | 21810.1 | 1 | Homo sapiens | ||
4 | G | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 11 | Chemie (NAG) | |||
5 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
G: 44 - 492 (UniProt: A0A0M3KKW9)
PDB | External Database | Details |
---|---|---|
Val 42 | - | expression tag |
Pro 43 | - | expression tag |
Ser 375 | His 242 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 86052.6 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 2433.3 | |
All* | Total formula weight | 88485.9 |