6OF8

Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CamKII-alpha hub domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	F, B, C, G, E...	Calcium/calmodulin-dependent protein kinase type II subunit alpha	polymer	135	15551.6	7	UniProt (Q9UQM7) Pfam (PF08332) In PDB	Homo sapiens (Human)	CaMK-II subunit alpha
2	F, E, A, D	POTASSIUM ION	non-polymer		39.1	5	Chemie (K)
3	C, E, A	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4		water	water		18.0	105	Chemie (HOH)

Sequence modifications

F, B, C, G, E, A, D: 345 - 475 (UniProt: Q9UQM7)

PDB	External Database	Details
Gly 341	-	expression tag
Pro 342	-	expression tag
His 343	-	expression tag
Met 344	-	expression tag
Asn 354	Thr 354	engineered mutation
Gln 355	Glu 355	engineered mutation
Asn 412	Thr 412	engineered mutation
Met 414	Ile 414	engineered mutation
His 464	Ile 464	engineered mutation
Met 467	Phe 467	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	108861.0
Non-Polymers*	Number of molecules	8
	Total formula weight	471.8
All*	Total formula weight	109332.8

*Water molecules are not included.