6NND
Structure of Dihydrofolate reductase from Mycobacterium tuberculosis in complex with NADPH and dihydrofolate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Dihydrofolate reductase | polymer | 159 | 17661.0 | 2 | UniProt (P9WNX1) Pfam (PF00186) In PDB | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | |
| 2 | A, B | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | A, B | COBALT (II) ION | non-polymer | 58.9 | 3 | Chemie (CO) | |||
| 4 | A, B | DIHYDROFOLIC ACID | non-polymer | 443.4 | 2 | Chemie (DHF) | |||
| 5 | A, B | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 6 | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35322.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 3130.8 | |
| All* | Total formula weight | 38452.8 |
