6MOB
Crystal structure of KIT1 in complex with DP2976 via co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Mast/stem cell growth factor receptor Kit | polymer | 312 | 35331.9 | 1 | UniProt (P10721) Pfam (PF07714) In PDB | Homo sapiens (Human) | SCFR, Piebald trait protein, PBT, Proto-oncogene c-Kit, Tyrosine-protein kinase Kit, p145 c-kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| 2 | A | NITRATE ION | non-polymer | 62.0 | 14 | Chemie (NO3) | |||
| 3 | A | N-{4-chloro-5-[1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl]-2-fluorophenyl}-N'-phenylurea | non-polymer | 465.9 | 1 | Chemie (JWY) | |||
| 4 | water | water | 18.0 | 311 | Chemie (HOH) |
Sequence modifications
A: 566 - 693 (UniProt: P10721)
A: 754 - 935 (UniProt: P10721)
A: 754 - 935 (UniProt: P10721)
| PDB | External Database | Details |
|---|---|---|
| Thr 694 | - | linker |
| Ser 753 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35331.9 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1334.0 | |
| All* | Total formula weight | 36665.9 |
