6LXE
DROSHA-DGCR8 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Ribonuclease 3 | polymer | 990 | 115390.6 | 1 | UniProt (Q9NRR4) Pfam (PF14622) Pfam (PF00636) Pfam (PF00035) In PDB | Homo sapiens (Human) | Protein Drosha,Ribonuclease III,RNase III,p241 |
2 | B, C | Microprocessor complex subunit DGCR8 | polymer | 773 | 86171.2 | 2 | UniProt (Q8WYQ5) Pfam (PF00035) In PDB | Homo sapiens (Human) | DiGeorge syndrome critical region 8 |
3 | A | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A: 391 - 1374 (UniProt: Q9NRR4)
PDB | External Database | Details |
---|---|---|
Gln 1045 | Glu 1045 | engineered mutation |
Gln 1222 | Glu 1222 | engineered mutation |
His 1375 | - | expression tag |
His 1376 | - | expression tag |
His 1377 | - | expression tag |
His 1378 | - | expression tag |
His 1379 | - | expression tag |
His 1380 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 287733.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 287863.8 |